Nicotine replacement therapy

There was a discussion at a recent morbidity meeting around the use of nicotine patches in critical care. Here’s the most recent evidence on the use of nicotine replacement therapy in critically ill patients:

Nicotine replacement therapy for agitation and delirium management in the intensive care unit: a systematic review of the literature.
Kowalski, M. et al, (2016) Journal of Intensive Care. Nov 15; 4:69 Full Text

Nicotine replacement therapy in the intensive care unit: a systematic review.
Wilby, K.J. & Harder, C.K., (2014) Journal of Intensive Care Medicine. 29 (1), pp.22-30 Abstract

There’s also a useful 10 minute podcast interview with an Intensivist from Australia that gives a basic overview of the topic: https://omny.fm/shows/essential-critical-care/andrew-udy

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Spontaneous breathing trial techniques

After the ward round on the 31/08/2017 there was a discussion around CPAP vs t-piece – here’s a recently published meta-analysis on the subject:

Burns, K.E.A. et al (2017) Trials directly comparing alternative spontaneous breathing trial techniques: a systematic review and meta-analysis.
Critical Care, 21(1),127. Full Text

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Fluid resus and pancreatitis

The following articles have been identified following the ward round on 31st August 2017 to provide some reading around fluid resuscitation in pancreatitis.

If you have any problems accessing these documents please use your NHS Athens username and password, or contact library.rph@lthtr.nhs.uk

Stigliano, S. et al, (2017) Early management of acute pancreatitis: A review of the best evidence.
Digestive and Liver Disease, 49 (6), pp. 585-594. Full Text

Singh, V.K. et al, (2017) An international multicenter study of early intravenous fluid  administration and outcome in acute pancreatitis.
United European Gastroenterology Journal, 5 (4), pp. 491-498. Full Text

Dick, J.F. 3rd, Gardner, T.B. & Merrens, E.J. (2016) Acute pancreatitis: New developments and strategies for the hospitalist.
Journal of Hospital Medicine, 11 (10), pp.724-729. Abstract

UK guidelines for the management of acute pancreatitis.
UK Working Party on Acute Pancreatitis (2005), available at:
http://www.bsg.org.uk/images/stories/docs/clinical/guidelines/pancreatic/pancreatic.pdf

Treat the Cause: A review of the quality of care provided to patients treated for acute pancreatitis.
National Confidential Enquiry into Patient Outcome and Death (2016), available at:
http://www.ncepod.org.uk/2016report1/downloads/TreatTheCause_fullReport.pdf

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Non-Invasive Ventilation Postextubation

The following articles have been identified following the ward round on 18th August 2017 to provide some reading around NIV following extubation.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

Ferrer et al (2009) Non-invasive ventilation after extubation in hypercapnic patients with chronic respiratory disorders: randomised controlled trial. Lancet. 2009 Sep 26;374(9695):1082-8 

Comments on this trial in:

ACP Journal Club. Noninvasive ventilation after extubation reduced respiratory failure and 90-day mortality in hypercapnic patients. Ann Intern Med. 2010 Feb 16;152(4):JC-24.

Leaving invasive ventilation behind The Lancet Volume 374, Issue 9695, 26 September–2 October 2009, Pages 1044-1045 

Non-invasive ventilation (NIV) immediately after extubation reduces ventilatory failure and 90-day mortality in patients with hypercapnia Thorax 65(7) 

Noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial Crit Care. 2013; 17(2): 

Trevisan CE, Vieira SR; (2008) Noninvasive mechanical ventilation may be useful in treating patients who fail weaning from invasive mechanical ventilation: a randomized clinical trial. Crit Care 2008; 12

Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis BJA: British Journal of Anaesthesia, Volume 109, Issue 3, 1 September 2012, Pages 305–314.

High-flow nasal cannulae for respiratory support in adult intensive care patients. Cochrane Database Syst Rev. 2017 May 30;5: 

Burns et al (2013) Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with respiratory failure. Cochrane Database Syst Rev. 2013 Dec 9;(12): 

Dynamed (2017) Weaning from mechanical ventilation 

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PACO2 levels in traumatic brain injury

The following articles have been identified following the ward round on 17th July 2017 to provide some reading around PaCO2 levels in traumatic brain injury.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

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Blood pressure management after intracerebral haemorrhage

The following articles have been identified following the ward round on 17th July 2017 to provide some reading around blood pressure management after intracerebral haemorrhage.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

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Sepsis management

The following articles have been identified to provide some reading around the management of sepsis for teaching the week beginning 10th July 2017.

The Surviving Sepsis International Guidelines were published in 2017, so only recent articles and web sites have been included in this topic overview.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

There are a number of additional resources available on the guidelines section of the Surviving Sepsis Campaign website which may be of additional interest.

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