Delirium and haloperidol

The following articles have been identified following the ward round on 26th October 2017 to provide some reading around delirium in CC and the use of haloperidol.

Mo, Y. & Yam, F.K. (2017) Rational use of second-generation antipsychotics for the treatment of ICU delirium.
Journal of Pharmacy Practice, 30 (1), pp:121-129. Abstract

Kishi, T. et al (2016) Antipsychotic medications for the treatment of delirium: a systematic review and meta-analysis of randomised controlled trials.
Journal of Neurology, Neurosurgery & Psychiatry. 87 (7), pp:767-74. Full Text

Schrijver, E.J. et al (2016) Efficacy and safety of haloperidol for in-hospital delirium prevention and treatment: A systematic review of current evidence.
European Journal of Internal Medicine. 27, pp:14-23. Abstract

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

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Acute respiratory distress syndrome

The following articles have been identified following the ward round on 26th October 2017 to provide some reading around ARDS.

Sharma S. (2010) Acute respiratory distress syndrome.
BMJ Clinical Evidence Nov 30; pii: 1511. Full Text

Walkey, A.J. et al (2017) Low tidal volume versus non-volume-limited strategies for patients with acute respiratory distress syndrome: a systematic review and meta-analysis.
Annals of the American Thoracic Society Aug 28. [Epub ahead of print]. Abstract

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

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Nicotine replacement therapy

There was a discussion at a recent morbidity meeting around the use of nicotine patches in critical care. Here’s the most recent evidence on the use of nicotine replacement therapy in critically ill patients:

Nicotine replacement therapy for agitation and delirium management in the intensive care unit: a systematic review of the literature.
Kowalski, M. et al, (2016) Journal of Intensive Care. Nov 15; 4:69 Full Text

Nicotine replacement therapy in the intensive care unit: a systematic review.
Wilby, K.J. & Harder, C.K., (2014) Journal of Intensive Care Medicine. 29 (1), pp.22-30 Abstract

There’s also a useful 10 minute podcast interview with an Intensivist from Australia that gives a basic overview of the topic: https://omny.fm/shows/essential-critical-care/andrew-udy

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Spontaneous breathing trial techniques

After the ward round on the 31/08/2017 there was a discussion around CPAP vs t-piece – here’s a recently published meta-analysis on the subject:

Burns, K.E.A. et al (2017) Trials directly comparing alternative spontaneous breathing trial techniques: a systematic review and meta-analysis.
Critical Care, 21(1),127. Full Text

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Fluid resus and pancreatitis

The following articles have been identified following the ward round on 31st August 2017 to provide some reading around fluid resuscitation in pancreatitis.

If you have any problems accessing these documents please use your NHS Athens username and password, or contact library.rph@lthtr.nhs.uk

Stigliano, S. et al, (2017) Early management of acute pancreatitis: A review of the best evidence.
Digestive and Liver Disease, 49 (6), pp. 585-594. Full Text

Singh, V.K. et al, (2017) An international multicenter study of early intravenous fluid  administration and outcome in acute pancreatitis.
United European Gastroenterology Journal, 5 (4), pp. 491-498. Full Text

Dick, J.F. 3rd, Gardner, T.B. & Merrens, E.J. (2016) Acute pancreatitis: New developments and strategies for the hospitalist.
Journal of Hospital Medicine, 11 (10), pp.724-729. Abstract

UK guidelines for the management of acute pancreatitis.
UK Working Party on Acute Pancreatitis (2005), available at:
http://www.bsg.org.uk/images/stories/docs/clinical/guidelines/pancreatic/pancreatic.pdf

Treat the Cause: A review of the quality of care provided to patients treated for acute pancreatitis.
National Confidential Enquiry into Patient Outcome and Death (2016), available at:
http://www.ncepod.org.uk/2016report1/downloads/TreatTheCause_fullReport.pdf

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Non-Invasive Ventilation Postextubation

The following articles have been identified following the ward round on 18th August 2017 to provide some reading around NIV following extubation.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

Ferrer et al (2009) Non-invasive ventilation after extubation in hypercapnic patients with chronic respiratory disorders: randomised controlled trial. Lancet. 2009 Sep 26;374(9695):1082-8  Full text

Comments on this trial in:

ACP Journal Club. Noninvasive ventilation after extubation reduced respiratory failure and 90-day mortality in hypercapnic patients. Ann Intern Med. 2010 Feb 16;152(4):JC-24. Full text

Leaving invasive ventilation behind The Lancet Volume 374, Issue 9695, 26 September–2 October 2009, Pages 1044-1045  Full text

Non-invasive ventilation (NIV) immediately after extubation reduces ventilatory failure and 90-day mortality in patients with hypercapnia Thorax 65(7)  Full text

Ornico et al (2013) Noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial Crit Care. 2013; 17(2):  Full text

Trevisan CE, Vieira SR; (2008) Noninvasive mechanical ventilation may be useful in treating patients who fail weaning from invasive mechanical ventilation: a randomized clinical trial. Crit Care 2008; 12 Full text

Glossop et al (2012) Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis BJA: British Journal of Anaesthesia, Volume 109, Issue 3, 1 September 2012, Pages 305–314. Full text

Corley et al (2017) High-flow nasal cannulae for respiratory support in adult intensive care patients. Cochrane Database Syst Rev. 2017 May 30;5:  Full text

Burns et al (2013) Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with respiratory failure. Cochrane Database Syst Rev. 2013 Dec 9;(12): Full text

Dynamed (2017) Weaning from mechanical ventilation Full text

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PACO2 levels in traumatic brain injury

The following articles have been identified following the ward round on 17th July 2017 to provide some reading around PaCO2 levels in traumatic brain injury.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

Go, SL & Singh, JM. (2013) Pro/con debate: Should PaCO2 be tightly controlled in all patients with acute brain injuries?  Critical Care, 17(202)  Full text

Dinsmore, J. (2013) Traumatic brain injury: an evidence-based review of management. Critical Care & Pain, 13(6)  Full text

Brain Trauma Foundation (2016) Guidelines for the Management of Severe Traumatic Brain Injury. 4th Edition Full text

Haddad, SH & Arabi, YM. (2012) Critical care management of severe traumatic
brain injury in adults. Scandinavian Journal of Trauma, Resuscitation and
Emergency Medicine, 20(12) Full text

The Association of Anaesthetists of Great Britain and Ireland (2006)
Recommendations for the Safe Transfer of Patients with Brain Injury.
London: The Association of Anaesthetists of Great Britain and Ireland Full text

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