Methylene blue complications

The following articles have been identified following the ward round on Friday 9th June 2017 to provide some reading around the use of methylene blue (methylthioninium chloride) and complications with anaesthesia.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

METHYLTHIONINIUM CHLORIDE BNF 2017

Methylthioninium chloride Proveblue 5 mg/ml solution for injection EMC 2016

Hypertension and Decreased Renal Blood Flow Following Methylene Blue Injection Birch, A; Boyce, W Anesthesia & Analgesia: September/October 1976

Risk of severe serotonin toxicity following co-administration of methylene blue and serotonin reuptake inhibitors: an update on a case report of post-operative delirium. Stanford et al. J Psychopharmacol. 2010 Oct;24(10):1433-8

Fatal methylene blue associated serotonin toxicity Top et al. Netherlands. The Journal of Medicine April 2014. 72 (3) 

 

Posted in Ward Round Update | Tagged | Leave a comment

Acetazolamide: in ventilator weaning

The following articles have been identified following the ward round on Friday 9th June 2017 to provide some reading around the role of Acetazolamide in ventilator weaning.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial. Faisy et al. JAMA. 2016 Feb 2;315(5):480-8

Comments on the above:

Acetazolamide and Invasive Mechanical Ventilation for Patients With COPD. [JAMA. 2016]

Acetazolamide and Invasive Mechanical Ventilation for Patients With COPD–Reply. [JAMA. 2016]

Acetazolamide and Invasive Mechanical Ventilation for Patients With COPD. [JAMA. 2016]

Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease or obesity-hypoventilation syndrome with metabolic alkalosis. A randomized trial. Rialp et al. Pulm Pharmacol Ther. 2017 Jun;44:30-37.  Abstract only.

Acetazolamide: a second wind for a respiratory stimulant in the intensive care unit? Heming et al. Critical Care 2012, 16:318 

Effectiveness of acetazolamide for reversal of metabolic alkalosis in weaning COPD patients from mechanical ventilation. Faisy et al. Intensive Care Med. 2010 May;36(5):859-63.  Abstract only

Posted in Ward Round Update | Tagged | Leave a comment

Treatments for Inhalation Injury

The following articles have been identified following the ward round on Friday 9th June 2017 to provide some reading around the combined use of N-acetyl-L-cysteine (NAC), salbutamol, heparin and sodium bicarbonate (NaHCO3) for the treatment of inhalation injury.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

Diagnosis and management of inhalation injury: an updated review Walker et al. Critical Care (2015) 19:351 

Inhaled Anticoagulation Regimens for the Treatment of Smoke Inhalation-Associated Acute Lung Injury: A Systematic Review Miller et al Crit Care Med. 2014 February ; 42(2): 413–419

Management of acute smoke inhalation injury Toon et al Crit Care Resusc. 2010 Mar;12(1):53-61.

Influence of nebulized unfractionated heparin and Nacetylcysteine in acute lung injury after smoke inhalation injury. Miller AC et al. J Burn Care Res, 30: 249-56, 2009. Abstract only available

Does a Nebulized Heparin/N-acetylcysteine Protocol Improve Outcomes in Adult Smoke Inhalation? Kashefi et al Plastic and Reconstructive Surgery – Global Open: June 2014 – Volume 2 – Issue 6 – p e165

Posted in Ward Round Update | Tagged | Leave a comment

Adaptive support ventilation: long-term weaning of ICU patients

The following articles have been identified following the ward round on Thursday 11th May 2017 to provide a general overview of the above.

If you have any problems accessing these documents please use your NHS Athens or contact library.rph@lthtr.nhs.uk

Adaptive Support Ventilation From Intubation to Extubation:
A Word of Caution

Response to Adaptive Support Ventilation From Intubation to Extubation: A Word of Caution (Chest. 2016;149(1):280-281.)

Posted in Ward Round Update | Tagged | Leave a comment

Metformin-induced acidosis

The following articles have been identified following the ward round on Tuesday 16th May 2017 to provide a general overview of the above.

If you have any problems accessing these documents please use your NHS Athens or contact library@lthtr.nhs.uk

Posted in Ward Round Update | Tagged , , | Leave a comment

Acute upper GI bleed

The following articles have been identified following the ward round on Tuesday 16th May 2017 to provide a general overview of the above.

If you have any problems accessing these documents please use your NHS Athens or contact library@lthtr.nhs.uk

 

Posted in Ward Round Update | Tagged | Leave a comment

Vasculitis in ICU

The following articles have been identified following the ward round on Tuesday 16th May 2017 to provide a general overview of the above.

If you have any problems accessing these documents please use your NHS Athens or contact library@lthtr.nhs.uk

Posted in Ward Round Update | Tagged , | Leave a comment